Research

We have a team of excellence researchers with PhD degree who, in addition to our cutting-edge technological capacities, allows us to create applied scientific knowledge in order to solve problems in the agribusiness.
CREAS supports entrepreneurship and enhanced competitiveness of the regional industry through developing and managing R&D and technology transfer projects.

Along with its activities and its strategic alignment with regional and country-wide public policies, it seeks to encourage public-private investment on R&D&i and programs aimed to increase healthy food consumption.

CREAS’ work goal is to provide technological solutions for the productive sector — which, based on excellence science and technology development, allow regional industry to increase productivity and competitiveness, responding in a dynamic, flexible, and convenient fashion within its scope of action. The aforementioned is performed around four current CREAS’ lines of work:

Line 1

To develop new and/or improved products, processes, and technology for competitive growth of food agribusiness through applied innovation mechanisms.

Line 2

Developing technologies and/or protocols aimed to strengthen packed food shelf life.

 

Line 3

Developing sustainable technology applied to obtain high added value compounds and products, from non-timber forestry products and from discards and waste from the food agribusiness.

Line 4

As a result of the aforementioned research lines, it is worth noting the Technology Transfer of knowledge generated to the productive sector (Management and Service Line).

National Interaction

CREAS is engaged with the different R&D&i institutions across the country. Some framework agreements for collaboration with national entities supporting and encouraging the goal of its work are mentioned below:

It has also developed several applied R&D projects together with over 100 companies from the productive sector, and interaction projects through commercial prospecting missions.


International Interaction

In the international arena, CREAS, from the very beginning, has stated the goal of defining and developing an international strategic collaboration plan which allows it to be on the edge of knowledge, having access, at the same time, to infrastructure and technological capabilities in a quick and effective way. It is for this reason that in many projects executed with CREAS we have maintained collaboration networks with foreign technological entities with a vast career in R&D on Food Science and Engineering, such as:

In 2017, CREAS turned 10 years, on the base of two big projects, 5-years each: The Initiation project, through which we achieved creating a Regional Center with legal status, clear goals and defined governance, and a Continuity project. With this project, CREAS is established as an institution committed to research, innovation, and technology transfer on healthier food. We are proud to say the result of this project was assessed as optimum by the external peer commission appointed by CONICYT.


Reports


Scientific Publications

Publications by the Research Team within the last 5 years on mainstream journals.


Field responses of potato to increased temperature during tuber bulking: Projection for climate change scenarios, at high-yield environments of Southern Chile.

Agricultural and Forest Meteorology, 239, 192-201.

Investigadores:

Carolina Lizana, Andrea Avila, Alejandro Tolaba y Juan Pablo Martínez.

Phosphorus deficiency modifies as translocation in the halophyte plant species Atriplex atacamensis.

Ecotoxicology and Environmental Safety, 139, 344-351.

Investigadores:

Delphine Vromman, Juan-Pablo Martínez, y Stanley Lutts.

Different responses in the expression of alginases, alginate polymerase and acetylation genes during alginate production by Azotobacter vinelandii under oxygen-controlled conditions.

Journal of Industrial Microbiology & Biotechnology, 1-11.

Investigadores:

Alvaro Díaz-Barrera, Nataly Maturana, Ivette Pacheco-Leyva, Irene Martínez y Claudia Altamirano.

Quinoa proteins (Chenopodium quinoa Willd.) fractionated by ultrafiltration using ceramic membranes: The role of pH on physicochemical and conformational properties.

Food and Bioproducts Processing, 102, 20-30.

Investigadores:

Rosa Navarro-Lisboa, Camila Herrera, Rommy N. Zúñiga, Javier Enrione, Fanny Guzmán, Silvia Matiacevich y Carolina Astudillo-Castro.

Purification of galacto-oligosaccharides (GOS) by three-stage serial nanofiltration units under critical transmembrane pressure conditions.

Chemical Engineering Research and Design, 117, 488-499.

Investigadores:

Andrés Córdova, Carolina Astudillo, Luciana Santibañez, Alfredo Cassano, René Ruby-Figueroa, y Andrés Illanes.

Effect of drum drying temperature on drying kinetic and polyphenol contents in pomegranate peel.

Journal of Food Engineering, 208, 19-27.

Investigadores:

Galaz, P., Monika Valdenegro, Cristian Ramírez, Helena Nuñez, Sergio Almonacid y Ricardo Simpson.

Genome-scale metabolic reconstruction for the insidious bacterium in aquaculture Piscirickettsia salmonis.

Bioresource technology, 223, 105-114.

Investigadores:

Pablo Fuentealba, Camila Aros, Yesenia Latorre, Irene Martínez, Sergio Marshall, Pau Ferrer, Joan Albiol y Claudia Altamirano.

Industrial avocado waste: Functional compounds preservation by convective drying process.

Journal of Food Engineering, 198, 81-90.

Investigadores:

Jorge Saavedra, Andrés Córdova, Rosa Navarro, Paulo Díaz-Calderón, Claudia Fuentealba, Carolina Astudillo-Castro, Lea Toledo, Javier Enrione y Lena Galvez.

Understanding the success of Page's model and related empirical equations in fitting experimental data of diffusion phenomena in food matrices.

Trends in Food Science & Technology, 62, 194-201.

Investigadores:

Ricardo Simpson, Cristian Ramírez, Helena Nuñez, Jaques, A. y Sergio Almonacid.

Inverse method for the simultaneous estimation of the thermophysical properties of foods at freezing temperatures.

Journal of Food Engineering, 191, 37-47.

Investigadores:

Iván Cornejo, Cornejo, G., Cristian Ramírez, Sergio Almonacid y Ricardo Simpson.

Technical feasibility of glucose oxidase as a prefermentation treatment for lowering the alcoholic degree of red wine.

American Journal of Enology and Viticulture, 68(3), 386-389.

Investigadores:

Pedro Valencia, Karen Espinoza, Cristian Ramirez, Wendy Franco y Alejandra Urtubia.

Production of combi-CLEAs of glycosidases utilized for aroma enhancement in wine.

Food and Bioproducts Processing, 94, 555-560.

Investigadores:

Katherine Ahumada, Paulina Urrutia, Andrés Illanes y Lorena Wilson.

Inhibition of enteropathogens adhesion to human enterocyte-like HT-29 cells by a dairy strain of Propionibacterium acidipropionici.

Beneficial microbes, 7(3), 431-441.

Investigadores:

Zárate, G., Palacios, J. M., Villena, J. y María Elvira Zúñiga-Hansen.

Industrial avocado waste: Functional compounds preservation by convective drying process.

Journal of Food Engineering, 198, 81-90.

Investigadores:

Jorge Saavedra, Andrés Córdova, Rosa Navarro, Paulo Díaz-Calderón, Claudia Fuentealba, Carolina Astudillo-Castro, Lea Toledo, Javier Enrione y Lena Galvez.

Arsenic distribution in shoots of the halophyte plant species Atriplex atacamensis growing in an extreme arid mining area from northern Chile.

Journal of Bioremediation & Biodegradation, 7(349), 2.

Investigadores:

Delphine Vromman, Bérengère Paternostre, Margarita Briceño, Carolina Teixeira-Cardoso, Alejandra Flores-Bavestrello, Nicolas Vanhecke, Mahendra Kumar, Juan-Pablo Martínez y Stanley Lutts.

The effects of drying processes on organoleptic characteristics and the health quality of food ingredients obtained from goldenberry fruits (Physalis peruviana).

Open Access Scientific Reports, 2(2), 1-7.

Investigadores:

Valdenegro, M., Almonacid, S., Henríquez, C., Lutz, M., Fuentes, L., & Simpson, R. (2013).

Effect on rat blood pressure of epitaondiol, diterpenoid isolated from the algae stypopodium flabelliforme of rapanui (chilean island territory in the pacific ocean). Investigadores:

Martinez, J. L., Vinet, R., Laurido, C., Jaimes, L., Vargas-Rueda, S., Rovirosa, J. y  San-Martin, A.

Inhibition of ethylene synthesis reduces salt-tolerance in tomato wild relative species Solanum chilense.

Journal of plant physiology, 210, 24-37.

Investigadores:

Emna Gharbiac, Juan-Pablo Martínez, Hela Benahmed, Gilles Lepoint, Brigitte Vanpee, Muriel Quinet y Stanley Lutts.

Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases.

PloS one, 9(9), e107749.

Investigadores:

Eduardo Caballero, Carmen Soto, Araceli Olivares, Claudia Altamirano.

Effect on rat blood pressure of epitaondiol, diterpenoid isolated from the algae stypopodium flabelliforme of rapanui (chilean island territory in the pacific ocean). Investigadores:

Martinez, J. L., Vinet, R., Laurido, C., Jaimes, L., Vargas-Rueda, S., Rovirosa, J. y  San-Martin, A.

Quinoa proteins (Chenopodium quinoa Willd.) fractionated by ultrafiltration using ceramic membranes: The role of pH on physicochemical and conformational properties.

Food and Bioproducts Processing, 102, 20-30.

Investigadores:

Rosa Navarro-Lisboa, Camila Herrera, Rommy N. Zúñiga, Javier Enrione, Fanny Guzmán, Silvia Matiacevich y Carolina Astudillo-Castro.

Inhibition of enteropathogens adhesion to human enterocyte-like HT-29 cells by a dairy strain of Propionibacterium acidipropionici.

Beneficial microbes, 7(3), 431-441.

Investigadores:

Zárate, G., Palacios, J. M., Villena, J. y María Elvira Zúñiga-Hansen.

Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer cell line.

Frontiers of Chemical Science and Engineering, 7(4), 482-489.

Investigadores:

Jacqueline Concha, Caroline Weinstein y María Elvira Zúñiga.

Purification of galacto-oligosaccharides (GOS) by three-stage serial nanofiltration units under critical transmembrane pressure conditions.

Chemical Engineering Research and Design, 117, 488-499.

Investigadores:

Andrés Córdova, Carolina Astudillo, Luciana Santibañez, Alfredo Cassano, René Ruby-Figueroa y Andrés Illanes.

Genome-scale metabolic reconstruction for the insidious bacterium in aquaculture Piscirickettsia salmonis.

Bioresource technology, 223, 105-114.

Investigadores:

Pablo Fuentealba, Camila Aros, Yesenia Latorre, Irene Martínez, Sergio Marshall, Pau Ferrer, Joan Albiol y Claudia Altamirano.

Methanisation of spent maqui berry pomace via enzymatic treatment.

Renewable Energy, 87, 326-331.

Investigadores:

Investigadores: Alejandra Cerda, María Eugenia Martínez, Carmen Soto, María Elvira Zúñiga y Paola Poirrier.

A new mechanism and kinetic model for the enzymatic synthesis of short-chain fructooligosaccharides from sucrose.

Biochemical Engineering Journal, 82, 158-165.

Investigadores:

Roberto Vega y María Elvira Zúñiga-Hansen.

The enhancement of antioxidant compounds extracted from Thymus vulgaris using enzymes and the effect of extracting solvent.

Food chemistry, 139(1), 138-143.

Investigadores:

Alejandra Cerda, María Eugenia Martínez, Carmen Soto, Paola Poirrier, José R. Perez-Correa, José R. Vergara-Salinas y María Elvira Zúñiga.

Effect of extraction conditions on total phenolic content and antioxidant capacity of pretreated wild Peumus boldus leaves from Chile.

Food and Bioproducts Processing, 92(3), 328-333.

Investigadores:

Carmen Soto, Eduardo Caballero, Eduardo Pérez y María Elvira Zúñiga.

Identification of the key mechanisms involved in the hydrolysis of fish protein by Alcalase.

Process Biochemistry, 49(2), 258-264.

Investigadores:

Pedro Valencia, Marlene Pinto y Sergio Almonacid.

Influence of ohmic heating/osmotic dehydration treatments on polyphenoloxidase inactivation, physical properties and microbial stability of apples (cv. Granny Smith).

Innovative Food Science & Emerging Technologies, 20, 198-207.

Investigadores:

Moreno, J., Simpson, R., Pizarro, N., Pavez, C., Dorvil, F., Petzold, G. y Bugueño, G.

Production of alginate by Azotobacter vinelandii grown at two bioreactor scales under oxygen-limited conditions.

Bioprocess and biosystems engineering, 37(6), 1133-1140.

Investigadores:

Alvaro Díaz-Barrera, Javiera Gutierrez, Fabiola Martínez, Claudia Altamirano.

Advances in improving mammalian cells metabolism for recombinant protein production.

Electronic Journal of Biotechnology, 16(3), 10-10.

Investigadores:

Claudia Altamirano, Julio Berrios, Mauricio Vergara y Silvana Becerra.

Improving Amphetamine Therapeutic Selectivity: N, N‐dimethyl‐MTA has Dopaminergic Effects and does not Produce Aortic Contraction.

Basic & clinical pharmacology & toxicology, 114(5), 395-399.

Investigadores:

Ramón Sotomayor-Zárate, Pablo Jara, Patricio Araos, Raúl Vinet, Gabriel Quiroz, Georgina M. Renard, Pedro Espinosa, Claudio Hurtado-Guzmán, Pablo R. Moya, Patricio Iturriaga-Vásquez, Katia Gysling y Miguel Reyes-Parada.

Differential effect of culture temperature and specific growth rate on CHO cell behavior in chemostat culture.

PloS one, 9(4), e93865.

Investigadores:

Mauricio Vergara, Silvana Becerra, Julio Berrios, Nelson Osses, Juan Reyes, María Rodríguez-Moyá, Ramón González y Claudia Altamirano.

Effects of spray drying conditions and the addition of surfactants on the foaming properties of a whey protein concentrate.

LWT-Food Science and Technology, 58(1), 109-115.

Investigadores:

Osorio, J., Monjes, J., Pinto, M., Ramírez, C., Simpson, R. y Vega, O.

Ohmic heating behaviour and electrical conductivity of two-phase food systems.

Innovative Food Science & Emerging Technologies, 4(1), 45-55.

Investigadores:

Zareifard, M. R., Ramaswamy, H. S., Trigui, M. y Marcotte, M.

The effect of processing conditions on the stability of fructooligosaccharides in acidic food products.

Food chemistry, 173, 784-789.

Investigadores:

Roberto Vega y María Elvira Zúñiga-Hansen

Characterization of pressurized hot water extracts of grape pomace: chemical and biological antioxidant activity.

Food chemistry, 171, 62-69.

Investigadores:

J.R. Vergara-Salinas, Mauricio Vergara, Claudia Altamirano, Álvaro González y J.R. Pérez-Correa

P-Coumaric acid reduces high glucose-mediated impairment of endothelium-dependent relaxation in rat aorta.

Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 13(3).

Investigadores:

Raúl Vinet, Patricio Araos, Juan Carlos Gentina, Marcela Knox y Leda Guzmán

Bradykinin and histamine‐induced cytosolic calcium increase in capillary endothelial cells of bovine adrenal medulla.

Cell biology international, 38(9), 1023-1031.

Investigadores:

Raúl Vinet, Magdalena P. Cortés, Rocío Álvarez y Marco Delpiano

Shellfish (Mussel) processing and components.

In Processing and impact on active components in food (pp. 447-454).

Investigadores:

Sergio Almonacid, Joselyn Bustamante, Ricardo Simpson y Marlene Pinto

Effect of extraction conditions on total phenolic content and antioxidant capacity of pretreated wild Peumus boldus leaves from Chile.

Food and Bioproducts Processing, 92(3), 328-333.

Investigadores:

Carmen Soto, Eduardo Caballero, Eduardo Pérez y María Elvira Zúñiga

Potential use of avocado oil on structured lipids MLM-type production catalysed by commercial immobilised lipases.

PloS one, 9(9), e107749.

Investigadores:

Eduardo Caballero, Carmen Soto, Araceli Olivares y Claudia Altamirano

Differential expression of ethylene biosynthesis genes in drupelets and receptacle of raspberry (Rubus idaeus).

Journal of plant physiology, 179, 100-105.

Investigadores:

Lida Fuentes, Liliam Monsalve, Luis Morales-Quintana, Mónika Valdenegro, Juan-Pablo Martínez, Bruno G. Defilippi y Mauricio González-Agüero

Study of effect of sodium alginate on potato starch digestibility during in vitro digestion.

Food Hydrocolloids, 44, 328-332.

Investigadores:

Cristian Ramírez, Camila Millon, Helena Nuñez, Marlene Pinto, Pedro Valencia, Cristian Acevedo y Ricardo Simpson

Novel modeling methodology for the characterization of enzymatic hydrolysis of proteins.

Process Biochemistry, 50(4), 589-597.

Investigadores:

Pedro Valencia, Karen Espinoza, Andrés Ceballos, Marlene Pinto y Sergio Almonacid

Effect of soil available water depletion on plant water status, fruit size and yield of avocado trees cv.'HASS'.

In VII International Symposium on Irrigation of Horticultural Crops 1038 (pp. 393-400).

Investigadores:

Investigadores: Ferreyra, R., Selles, G., Gil, P., Celedon, J. y Maldonado, P.

Characterization of pressurized hot water extracts of grape pomace: chemical and biological antioxidant activity.

Food chemistry, 171, 62-69.

Investigadores:

J.R. Vergara-Salinas, Mauricio Vergara, Claudia Altamirano, Álvaro González y J.R. Pérez-Correa.

Assessment of antiproliferative activity of pectic substances obtained by different extraction methods from rapeseed cake on cancer cell lines.

Carbohydrate polymers, 117, 923-932.

Investigadores:

M. Cobs-Rosas, J. Concha-Olmos, C. Weinstein-Oppenheimer y María Elvira Zúñiga-Hansen

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